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Mounjaro (tirzepatide) Disease area(s): Metabolic diseases Manufacturer(s): Eli Lilly and Company 2024 Sales (USD): $11.54 billion Why it sold so well: Eli Lillys dual GIP and GLP-1 receptor agonist for type 2 diabetes, Mounjaro, experienced exceptional growth in 2024, with global sales more than doubling to $11.54 billion

Leptin and melanocortin receptors (MCRs) have been linked to glucose regulation in peripheral tissues through the medial hypothalamus

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