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These data suggest that the route of B-cell stimulation is a major determinant of ferroptosis vulnerability, and that human peripheral blood B-cells require GPX4 upon EBV infection or with combinatorial B-cell receptor activation

Growth Hormone Sensitization: Increases GH receptor expression and enhances JAK2/STAT signaling (PMC6271067)

Principal effect modifiers are speculated to be differences in patient populations (peri-operative CABG vs PCI vs medically managed acute myocardial infarction) as well as resultant ischemic burden (Furat et al