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10.1093/toxsci/kfaa060 421 SvenssonE.Horvth-PuhE.ThomsenR

Journal of Autism and Developmental Disorders , 54(3), 123134

According to a 2020 review, melanosis coli is a reversible condition

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This varies on a case-by-case basis with some people losing a great deal of weight initially and then tapering off and others slowly losing weight over a longer period