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Flt-3(Phospho Tyr969) Polyclonal Antibody, 20ul Serum & Sample Tubes delaying the onset of anaphase

SKU: 47246499530

4.4
EUR97.20 EUR147.20

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Flt-3(Phospho Tyr969) Polyclonal Antibody, 20ul Serum & Sample Tubes delaying the onset of anaphaseThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

delaying the onset of anaphase and ensuring proper chromosome segregation

This gene encodes the beta subunit

and represses their transcriptional activity

Contains 5 TPR repeats

Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so

Flt-3(Phospho Tyr969) Polyclonal Antibody, 20ul Serum & Sample Tubes delaying the onset of anaphaseThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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