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Lets break it down: The Science Stuff (Simplified) Semaglutide mimics one hormone (GLP-1) Tirzepatide mimics two (GLP-1 + GIP) Both help regulate appetite, insulin, and blood sugar They're available as injectables , and in some programs including Josie you may be offered compounded oral tablets if appropriate

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In an MDA-MB-231 xenograft model, PRO achieved a TGI of 36.3% (vs PBS), whereas iPR reached 62.3% (5 M) and 81.5% (8 M) after 21 days (vs PBS), supporting a quantitatively stronger in vivo benefit than the parent PROTAC at matched/near-matched dosing

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