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La grande majorit des donnes provient d'tudes in vivo ralises sur des modles murins et de rat, ainsi que d'expriences in vitro sur des cultures cellulaires

262,263,264 Specific competitive inhibitor of NAMPT could ameliorate the immunity or inflammatory disorders, including DSS-induced colitis, arthritis via reducing intracellular NAD + levels in inflammatory cells and circulating inflammatory cytokines, including IL-1beta, TNF-alpha, and IL-6

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