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Development of GLP-1 Drugs Decades after the discovery of the natural hormone, there are now several available GLP-1 drugsor GLP-1 receptor agoniststhat can be used to treat diabetes, obesity, and other conditions

Reduced appetite often leads to lower overall fluid intake, while nausea or gastrointestinal changes can further impact hydration levels

RO7204239 is being researched for its potential to strengthen the muscles of spinal muscular atrophy patients

This happened long before any blood glucose could be detected

As per Bradford Hills criteria 41 , the biological plausibility through GLP-1R expression in the nervous system and temporal consistency in time-to-onset analysis support potential causality, but confounding factors inherent to spontaneous reporting systems preclude definitive conclusions