NPC1 Rabbit Polyclonal Antibody, 50ul Transporters involved in leukocyte transmigration

involved in leukocyte transmigration

This gene encodes a member of the RAS-like small GTP-binding protein superfamily

CoV uses its spike protein to recognize ACE2 as its receptors and mediate membrane fusion and virus entry into host cells(PMID: 32221306)

An important paralog of this gene is TNFAIP8L2

most of which are potentially secreted molecules

NPC1 Rabbit Polyclonal Antibody, 50ul Transporters involved in leukocyte transmigrationThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments