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UBE2W Polyclonal Antibody, 50ul Enzyme Activity Assays and the loop between S5

SKU: 49009152986

4.3
PLN185.00 PLN221.00

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UBE2W Polyclonal Antibody, 50ul Enzyme Activity Assays and the loop between S5This gene encodes a nuclear localized ubiquitin conjugating enzyme (E2) that, along with ubiquitin activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple

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Description

and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD)

and undergoes ubiquitination and proteasome-med

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Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders

The enzyme is involved in DNA repair and chromosomal DNA replication

UBE2W Polyclonal Antibody, 50ul Enzyme Activity Assays and the loop between S5This gene encodes a nuclear localized ubiquitin conjugating enzyme (E2) that, along with ubiquitin activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple

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