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209 SIRT4 modulates the efficiency of OXPHOS by regulating ANT2 and its overexpression is associated with elevated ATP levels, while its deficiency is linked to mitochondrial uncoupling, resulting in increased oxygen consumption

All experimental procedures adhered to the guidelines of the institutional Ethics Committee and followed recommendations for the ethical care and use of laboratory animals

It is now widely accepted that chronic inflammation contributes to the pathogenesis of neurodegenerative disorders, including AD (Di Benedetto et al., 2022

PLoS ONE 12:e0182261

This dependency can also lead to the development of severe negative effects as well as potentially life-threatening cessation symptoms if a person tries to quit using Cymbalta too abruptly, and without proper guidance

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