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Results of MDR-1 modification trial indicate that granulocyte/ macrophage colony-forming unit cells do not contribute to post transplant hematopoietic recovery following intensive systemic therapy

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Confirmed a 50% reduction in depressive behaviours in pre-clinical models via TREK-1 modulation, validated the novel antidepressant mechanism distinct from monoamine pathways, and reviewed the full Spadin/PE22-28 mechanistic landscape

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