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MK-4827 Tosylate Size:Solid 2 mg and induces IL-8 secretion

SKU: 54750148268

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MK-4827 Tosylate Size:Solid 2 mg and induces IL-8 secretionNiraparib, also know as MK 4827, is an inhibitor of poly (ADP ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base excision repair (BER) pathway. Product information CAS Number: 1038915 73 9 Molecular Weight: 492. 59 Formula:

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Description

and induces IL-8 secretion

[Epub ahead of print] PubMed PMID: 27352067

demostrating excitation and emission maxima are 494 and 520 nm

decreases thermal and mechanical pain

1946833-91-5 (mesylate)

MK-4827 Tosylate Size:Solid 2 mg and induces IL-8 secretionNiraparib, also know as MK 4827, is an inhibitor of poly (ADP ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base excision repair (BER) pathway. Product information CAS Number: 1038915 73 9 Molecular Weight: 492. 59 Formula:

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