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Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Translocation t(X

SKU: 78699962339

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Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Translocation t(XRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

Translocation t(X

which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport

CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

Mutations in GATA4 have been associated with cardiac septal defects

Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Translocation t(XRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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