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Lower doses (1020 mg) are advisable in severe hepatic impairment, and liver enzymes should be monitored during prolonged therapy

In recent years, GLP-1 receptor agonists have gained attention for their role in managing diabetes and supporting weight loss

Emerging evidence indicates a cyclical pattern of use among GLP-1 consumers, with our research suggesting 60% of GLP-1 users discontinue within six months

Tirzepatide and semaglutide should be prescribed as first-choice medications and liraglutide and naltrexonebupropion as second-line treatments in individuals with obesity and glycemic alterations (Fig