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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

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Accumulating evidence further indicates that carotenoid supplementation reduces lipid peroxidation, attenuates oxidized LDL levels, and protects against early atherosclerotic changes (7981)