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Semaglutide binds primarily to GLP-1 receptors, while tirzepatide activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptorsmaking it a dual-action therapy

New cells are formed throughout life, but older cells usually are not lost

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GLP-1 receptor agonists include medications such as semaglutide, dulaglutide, and liraglutide, which are typically administered by subcutaneous injection (though oral semaglutide is available)