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It was previously recognized that concatenation of existing domains through gene fusion, also known as protein domain mosaicism, encodes new functions in more complex organisms (Patthy, Thus, two modes of acquisition of increased protein complexity have been demonstrated to date: protein domain mosaicism (Patthy, In this study, we analyzed incorporation of disulfide-based redox switches into three protein families

Metabolomics 8 , 12041217 (2012)

While both peptides bind to the GHRH receptor, their different structures and durations of action could potentially influence downstream signaling cascades in slightly different ways