Mcl-1 Monoclonal Antibody, 50ul sgRNA Library Construction This gene was identified by

This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1

such read-through transcripts are contained in GeneID 407977

The protein localizes to the nucleus and the cytoplasm

via this interaction

The phosphorylation of the complex by CDC2 kinase reduces the helicase activity

Mcl-1 Monoclonal Antibody, 50ul sgRNA Library Construction This gene was identified byThis gene encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.