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HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09890] Cell Culture Flasks Mutations in this gene are

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HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09890] Cell Culture Flasks Mutations in this gene areThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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Description

Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease)

signal transduction and cell polarity control

The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

also known as seven transmembrane receptors

HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09890] Cell Culture Flasks Mutations in this gene areThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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