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IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulation

SKU: 3621995601

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IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulationThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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Description

May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles

This gene maps to a region of 19q13

Over-expressed in breast cancer

The encoded protein may be involved in regulating cell death

blood clotting

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets May be involved in modulationThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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