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SKU: 34836565763

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A separate 2025 narrative review flagged theoretical concerns about pathologic new blood vessel formation, which is the basis for the cancer-history caution below

HRES-1/RAB4-mediated depletion of DRP1 impairs mitochondrial homeostasis and represents a target for treatment in SLE

p53 tumour-suppressor caution Because FOXO4-DRI intervenes in the p53 pathway, which is critical for tumour suppression, there is theoretical concern that interfering with p53 dynamics might carry oncogenic risk