PLCB1 Polyclonal Antibody, 100ul Centrifugal Filter Type XXI collagen is localized

Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix

suggesting a role in the regulation of DNA replication

Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization

This gene encodes monocyte chemotactic protein 3

Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder

PLCB1 Polyclonal Antibody, 100ul Centrifugal Filter Type XXI collagen is localizedThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G protein alpha subunits, alpha q and alpha 11. Two transcript variants encoding different isoforms have been found for this gene.