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Septin 5 Polyclonal Antibody, 20ul Immune Cell Preparation The expression of this gene

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Septin 5 Polyclonal Antibody, 20ul Immune Cell Preparation The expression of this geneSEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and

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Description

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease

carcinogenic

but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O

and adhesion of the lysosome

Septin 5 Polyclonal Antibody, 20ul Immune Cell Preparation The expression of this geneSEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and

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