Neuregulin-3 Polyclonal Antibody, 100ul PCR Series Fusion of the N-terminus of

Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein

It may play a role in tumor cell metastasis

cyclin L1 can be overexpressed and is therefore often considered a proto-oncogene

p53 and BRCA1

In the developing cortex

Neuregulin-3 Polyclonal Antibody, 100ul PCR Series Fusion of the N-terminus ofNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to