HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix Recognizes the substrate consensus sequence

Recognizes the substrate consensus sequence

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

DLG-like (see DLG1

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

probably to asymmetric dimethylarginine

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix Recognizes the substrate consensus sequenceHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.