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doi: 10.3389/fnut.2025.1484827 Received 22 August 2024 Accepted 07 March 2025 Published 24 March 2025 Volume 12 - 2025 Edited by Eric Gumpricht, Independent Researcher, Gilbert, AZ, United States Reviewed by Chlo Berland, Universit Paris Cit, France Meng Zhao, University of California, Davis, United States Updates Copyright 2025 Sun, Liu, Yuan, Rong, Pang and Li

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As blood glucose continues to decline below 54 mg/dL (the threshold for clinically significant hypoglycemia), neuroglycopenic symptoms emerge due to insufficient glucose delivery to the brain