tirzepatide gip/glp-1 Insights into the Mechanism of Action of Tirzepatide: A Narrative Review Research Progress on the GIP/GLP-1

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The exception is the brain and spinal cord, where it only penetrates if the meninges (the membranes that enclose the brain and spinal cord) are inflamed

J Pharmacol Exp Ther 2012;340:539-48

By mimicking the GLP-1 hormone, it plays a vital role in controlling appetite and insulin release, which can lead to significant reductions in body mass and improved metabolic health