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Although a basal level of radical production is important for proper physiological function [5], overexpression of radical species, either via increased production or decreased antioxidant defense, can result in oxidative damage to lipids, proteins, and nucleic acids, all of which may contribute to the pathophysiology of disease [6]

doi: 10.1016/S0021-9258(18)99004-6 120 RushmoreT

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Research indicates an average weight loss of 1.1 kg over 12-24 weeks, though individual responses vary considerably