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Certain children may be eligible to take DUPIXENT once every 4 weeks

In contrast, weight loss magnitude during the pre-landmark period was not significantly associated with post-landmark all-cause mortality ( P = 0.14), the composite cardiovascular endpoint ( P = 0.55), incident cerebrovascular disease ( P = 0.25), incident heart failure ( P = 0.89), or incident valvular or rheumatic heart disease ( P = 0.43) (Fig

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In patients with MASH and liver fibrosis (stages F1--F3), there was an apparent beneficial effect of icosabutate on surrogate histological endpoints, particularly fibrosis improvement, although the prespecified primary endpoint of MASH resolution without worsening of fibrosis was not met [206]

It was developed specifically as a selective secretagogue, designed to trigger GH release while avoiding the hormonal "noise" (cortisol, prolactin) seen with earlier GHRPs